PeptideCalculations
Nonapeptide · 5 mg vials

DSIP calculator

DSIP is a nine-amino-acid peptide first isolated from rabbits in the 1970s. Human sleep trials from the 1980s and 90s gave about 25 nmol/kg intravenously (roughly 1.5 mg for a 70 kg adult) and found weak, inconsistent effects.

mL
Draw to
—units
— mL on a U-100, 1 mL barrel
Concentration
—mg/mL
— mcg per unit
Doses in the vial
—
of
DSIP dosage
25 nmol/kg IV (about 1.5 mg at 70 kg)per dose · clinical trial (Bes et al. 1992, Neuropsychobiology, 16 chronic insomnia patients, double-blind, 3 afternoon doses)
Frequency
nightly or 3 to 4 nights a week
Timing
30 to 60 minutes before bed (community); the trial dosed in the afternoon
Cycle
2 to 4 weeks, then a break; the trials were 3 nights
Route
subcutaneous, abdomen; the trials were intravenous
Easy mix
5 mg + 2 mL = 2.5 mg/mL, so 250 mcg = 0.1 mL = 10 units, 100 mcg = 4 units and 300 mcg = 12 units. One vial is 20 doses at 250 mcg.

Full DSIP dosage chart →

DSIP units chart

5 mg vial. Rows are doses; columns show the units to draw on a U-100 syringe at each water volume.

5 mg vial + 2 mL = 2.5 mg/mL (2,500 mcg/mL, 25 mcg per unit on U-100)
DosemLU-100 unitsDoses per vial
100 mcg0.04450
200 mcg0.08825
250 mcg0.11020
500 mcg0.22010
1 mg0.4405
2 mg0.8802
2.5 mg11002
5 mg22001

Other mixes: 5 mg + 1 mL · 5 mg + 3 mL

About the DSIP math

DSIP, delta sleep-inducing peptide, is a nine-amino-acid peptide first isolated from rabbit brain. Research listings are almost always 5 mg vials of lyophilized powder. With one vial size, the solvent volume is the only variable, and the example amount of 100 mcg shows how quickly small draws become hard to read at high concentration. A 5 mg vial with 1 mL of bacteriostatic water is 5 mg/mL, or 5,000 mcg/mL. A 100 mcg draw is 0.02 mL, or just 2 units on a U-100 syringe, and the vial holds 50 of them. With 2 mL the concentration is 2,500 mcg/mL and the same draw is 4 units. With 2.5 mL it is 2,000 mcg/mL and 100 mcg is 5 units, while 200 mcg is 10 units. With 5 mL it is 1,000 mcg/mL, so 100 mcg is a comfortable 10 units, but 5 mL will not fit in a 3 mL vial. The draw count stays at 50 for 100 mcg in every case.

DSIP questions

How much DSIP should I take for sleep?

Community use is 100 to 300 mcg subcutaneously 30 to 60 minutes before bed. The published trials used about 1.5 mg intravenously and still found only weak effects, so do not expect the small dose to knock you out. Start at 100 mcg.

How many units is 100 mcg of DSIP?

At 2.5 mg/mL (5 mg in 2 mL) 100 mcg is 4 units and 250 mcg is 10 units. With 1 mL of water, 100 mcg is 2 units, which is hard to read, so use 2 mL.

How many units is 100 mcg of DSIP at 5 mg in 2.5 mL?

5 mg divided by 2.5 mL is 2 mg/mL, or 2,000 mcg/mL. 100 mcg divided by 2,000 mcg/mL is 0.05 mL. On a U-100 syringe 0.05 mL is 5 units.

How much bacteriostatic water for a 5 mg vial of DSIP?

Any volume the vial holds. 1 mL gives 5 mg/mL, 2 mL gives 2.5 mg/mL and 3 mL gives 1.67 mg/mL (rounded). A 200 mcg draw is 4 units, 8 units or 12 units at those three concentrations.

How many 200 mcg draws are in a 5 mg vial of DSIP?

5 mg is 5,000 mcg, and 5,000 divided by 200 is 25 draws. With 2 mL of solvent (2,500 mcg/mL) each 200 mcg draw is 0.08 mL, or 8 units.

Brands we recommend for DSIP. We are independent and have no affiliation with any brand: no affiliate links, no referral codes, no paid placements. These are the suppliers whose testing and certificates hold up when we check them.