PeptideCalculations
growth hormone secretagogue (ghrelin receptor agonist) · studied for growth hormone release (human studies from 1990 on), appetite, heart and tissue protection (animal studies)

GHRP-6 dosage

GHRP-6 is the original growth hormone releasing peptide, shown in 1990 to release GH in healthy men at IV doses of 0.1 to 1 mcg/kg with no adverse effects in that study. It is also the hungriest of the family because it hits the ghrelin receptor hard. Users commonly inject 100 to 300 mcg under the skin two to three times daily, fasted, for 8 to 12 weeks, often timed before meals they want to eat big. It was never approved.

0.1 mcg/kg to 1 mcg/kgper single dose

Basis: published study (Bowers et al., JCEM 1990, 18 healthy men, IV). dose-dependent GH release, about 7 to 70 mcg for a 70 kg adult

How often
two to three times daily
When
fasted: morning, post-workout and before bed; 30 minutes or more before a meal if the goal is appetite
How long
8 to 12 weeks, then 2 to 4 weeks off
Route
subcutaneous, abdomen
Storage
lyophilized: fridge or freezer; reconstituted: fridge, commonly used within 4 weeks (commonly reported)

Dose ranges by source

RangePerBasisNote
0.1 mcg/kg to 1 mcg/kgsingle dosepublished study (Bowers et al., JCEM 1990, 18 healthy men, IV)dose-dependent GH release, about 7 to 70 mcg for a 70 kg adult
100 mcg to 300 mcgdose, 2 to 3 times dailycommonly reportedfasted; 100 mcg is commonly called the saturation dose

Titration schedule

Step up on this schedule; stay a step longer if side effects are rough.

WeeksDose
1100 mcg at bedtime
2-12100 to 300 mcg, 2 to 3 times daily

GHRP-6 dose to units chart

5 mg vial + 2.5 mL bacteriostatic water = 2 mg/mL (20 mcg per unit on a U-100 insulin syringe). 5 mg + 2.5 mL = 2 mg/mL, so 100 mcg = 0.05 mL = 5 units; 200 mcg = 10 units, 300 mcg = 15 units. A 10 mg vial with 5 mL gives the same 2 mg/mL.

DosemLUnits (U-100)Doses per vial
0 mcg0.00010.0150000
0 mcg0.00010.0120000
1 mcg0.00030.0310000
1 mcg0.00050.055000

Different vial or water? Full 5 mg + 2.5 mL table or set your own numbers below.

mL
Draw to
—units
— mL on a U-100, 1 mL barrel
Concentration
—mg/mL
— mcg per unit
Doses in the vial
—
of

Commonly stacked with

Side effects

Before you start. Human dosing is not established beyond single-dose studies; the daily ranges are user protocols and there are no phase 3 trials for any use. The hunger is real and can wreck a cut, and cortisol goes up at higher doses. Avoid with active cancer or a cancer history. Not medical advice; start low and talk to a clinician.

GHRP-6 dosage questions

How much GHRP-6 should I take?

The 1990 study used 0.1 to 1 mcg/kg IV, up to about 70 mcg for a 70 kg adult. Users commonly inject 100 to 300 mcg two to three times daily, fasted. On a 5 mg vial in 2.5 mL, 100 mcg is 5 units.

Does GHRP-6 increase appetite?

Strongly. It is a ghrelin mimic and most users report intense hunger 15 to 30 minutes after a shot. People bulking time it before meals; people cutting pick ipamorelin instead.

Can I take GHRP-6 with CJC-1295?

That is the standard pairing: 100 mcg of GHRP-6 with 100 mcg of CJC-1295 no DAC in one syringe, two to three times daily, fasted. The 1990 study showed GHRP and GHRH act synergistically, which is the basis for the stack. Keep both fasted.

Sources

  1. Bowers et al., J Clin Endocrinol Metab 1990, Growth hormone-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone (PMID 2108187)
  2. Peptide Protocol Wiki, GHRP-6 overview and protocol quick reference

Brands we recommend for GHRP-6. We are independent and have no affiliation with any brand: no affiliate links, no referral codes, no paid placements. These are the suppliers whose testing and certificates hold up when we check them.

This page is an educational summary of published labels, trials and commonly reported use. It is not medical advice and does not replace a clinician.