PeptideCalculations
GLP-1/GIP/glucagon triple agonist · 5 mg / 10 mg / 20 mg vials

Retatrutide calculator

Retatrutide is Eli Lilly's triple agonist, still in phase 3 and not approved anywhere. The phase 2 trial in NEJM tested 1, 4, 8 and 12 mg once weekly for 48 weeks and saw 8.7% to 24.2% weight loss against 2.1% on placebo.

mL
Draw to
—units
— mL on a U-100, 1 mL barrel
Concentration
—mg/mL
— mcg per unit
Doses in the vial
—
of
Retatrutide dosage
1 mg to 12 mgper week · clinical trial (phase 2, Jastreboff et al., NEJM 2023)
Frequency
once weekly
Timing
same day each week, any time of day
Cycle
continuous while in use; phase 2 ran 48 weeks, phase 3 (TRIUMPH) runs 80 weeks
Route
subcutaneous, abdomen or thigh; rotate sites
Easy mix
10 mg + 2 mL = 5 mg/mL, so 1 mg = 0.2 mL = 20 units; 2 mg = 40 units, 4 mg = 80 units. A 5 mg vial with 1 mL gives the same 5 mg/mL.

Full Retatrutide dosage chart →

Retatrutide units chart

10 mg vial. Rows are doses; columns show the units to draw on a U-100 syringe at each water volume.

10 mg vial + 2 mL = 5 mg/mL (5,000 mcg/mL, 50 mcg per unit on U-100)
DosemLU-100 unitsDoses per vial
100 mcg0.022100
200 mcg0.04450
250 mcg0.05540
500 mcg0.11020
1 mg0.22010
2 mg0.4405
2.5 mg0.5504
5 mg11002
10 mg22001

Other mixes: 10 mg + 1 mL · 10 mg + 3 mL · 5 mg + 2 mL · 20 mg + 2 mL

Retatrutide questions

Retatrutide dosage chart?

Trial doses were 1, 4, 8 and 12 mg once weekly, with the higher arms starting at 2 mg and stepping up every 4 weeks. The commonly reported self-dosing ladder is 0.5 to 1 mg for 4 weeks, 2 mg, 4 mg, 6 mg, then 8 mg. On a 10 mg vial in 2 mL that is 10 to 20 units, 40, 80, 120 (two draws) and 160 units.

How much retatrutide should I start with?

The trial arms with the fewest stomach problems started at 2 mg or lower. Most self-reported users start at 0.5 mg to 1 mg and hold 4 weeks. Starting at 4 mg is where the trial saw the worst early nausea.

How much bacteriostatic water for a 10 mg vial of Retatrutide?

Any volume the vial holds. 10 mg in 1 mL is 10 mg/mL, in 2 mL is 5 mg/mL and in 3 mL is 3.333 mg/mL. The water changes the units per dose, not the amount of peptide.

Brands we recommend for Retatrutide. We are independent and have no affiliation with any brand: no affiliate links, no referral codes, no paid placements. These are the suppliers whose testing and certificates hold up when we check them.