tripeptide antioxidant (Glu-Cys-Gly) · studied for oxidative stress, liver support, Parkinson's symptom pilot, skin lightening (IV clinics)

Glutathione dosage

Glutathione is a three-amino-acid antioxidant your cells make, sold in 200 to 1,500 mg vials. Clinic IV doses run 600 to 1,200 mg per session; the best controlled trial gave 1,400 mg IV three times a week for 4 weeks and was well tolerated with a mild, non-significant effect. Subcutaneous use is 200 to 400 mg two or three times a week. Oral glutathione is poorly absorbed, which is why people inject it.

By the Peptide Calculations editors · Updated 2026-10-19

1,400 mg IV three times a weekper infusion

Basis: clinical trial (Hauser et al. 2009, Movement Disorders, 21 Parkinson's patients, randomized, double-blind, 4 weeks). well tolerated, no safety concerns, no significant difference from placebo

How often: 2 to 3 times a week
When: any time; evening is common because some people feel sleepy after
How long: 4 to 8 weeks, then reassess; clinics run ongoing weekly sessions
Route: subcutaneous (abdomen, slow push) or IV in a clinic; intramuscular on the Indian label
Storage: lyophilized: fridge, protect from light; reconstituted: fridge, use within 3 to 7 days (commonly reported), much shorter than peptides

Dose ranges by source

Range	Per	Basis	Note
1,400 mg IV three times a week	infusion	clinical trial (Hauser et al. 2009, Movement Disorders, 21 Parkinson's patients, randomized, double-blind, 4 weeks)	well tolerated, no safety concerns, no significant difference from placebo
600 mg to 1,200 mg IV	infusion	commonly reported	clinic drips 1 to 3 times a week; the Indian label for injectable glutathione (Maxiliv) is 300 to 600 mg daily IV or IM for liver indications
200 mg to 400 mg subcutaneous	injection	commonly reported	2 to 3 times a week, 4 to 8 weeks

Glutathione dose to units chart

600 mg vial + 3 mL bacteriostatic water = 200 mg/mL (2,000 mcg per unit on a U-100 insulin syringe). 600 mg + 3 mL = 200 mg/mL, so 200 mg = 1 mL = 100 units (a full insulin syringe). 200 mg/mL is near the top of what dissolves; swirl, do not shake, and use within days because reduced glutathione oxidizes fast.

Dose	mL	Units (U-100)	Doses per vial
1,000 mg	5	500	0
1,400 mg	7	700	0

Different vial or water? Full 600 mg + 3 mL table or set your own numbers below.

Commonly stacked with

NAD+ 750 mg over 6 hours IV

Side effects

injection site stinging and swelling
sulfur smell or taste
flushing
nausea or cramping
rare allergic reactions, more often with IV

Before you start. It is not FDA approved for injection and the IV skin-lightening use has drawn safety warnings from several regulators. Reduced glutathione oxidizes within days in solution, so old vials are mostly inactive. People with sulfite or sulfur sensitivity and asthma should be careful, since inhaled glutathione has triggered bronchospasm. Not medical advice. Talk to a clinician and start low.

Glutathione dosage questions

How much glutathione to inject subcutaneously?

200 to 400 mg two or three times a week is the common range. At 200 mg/mL that is a full 1 mL syringe per 200 mg, so split 400 mg across two sites. Push slowly; it stings.

What is the IV glutathione dose?

Clinics give 600 to 1,200 mg per drip, one to three times a week. The controlled Parkinson's pilot used 1,400 mg three times a week for 4 weeks with no safety issues. The Indian injectable label is 300 to 600 mg a day for liver indications.

How long does reconstituted glutathione last?

Days, not weeks. Reduced glutathione oxidizes once in water, faster with light and warmth. Mix what you will use within about a week, keep it cold and dark, and discard it if it turns cloudy or yellow.

Is injecting glutathione better than taking it orally?

Oral glutathione is broken down in the gut and raises blood levels little, which is the reason clinics inject it. Injection reliably raises plasma levels. Whether that changes anything you can feel is not shown in a controlled trial.

Sources

Brands we recommend for Glutathione. We are independent and have no affiliation with any brand: no affiliate links, no referral codes, no paid placements. These are the suppliers whose testing and certificates hold up when we check them.

Licensed Peptides two accredited labs on every lot, certificates public, card and Apple Pay checkout
Core Peptides long track record, public certificates, wide catalog
Ascension Peptides public third-party testing, clear pricing

This page is an educational summary of published labels, trials and commonly reported use. It is not medical advice and does not replace a clinician.